亚硫酸氢钠对叙利亚仓鼠胚胎细胞的转化作用。
Transformation of Syrian hamster embryo cells by sodium bisulfite.
作者信息
DiPaolo J A, DeMarinis A J, Doniger J
出版信息
Cancer Lett. 1981 Apr;12(3):203-8. doi: 10.1016/0304-3835(81)90069-0.
PMID:7260891
Abstract
Exposure at neutral pH of Syrian hamster embryo cells (HEC) to non-lethal, non-mutagenic doses of bisulfite, the physiological form of SO2, causes a dose-dependent increase in transformation. When bisulfite is used in combination with UV irradiation, the induction of transformation is not synergistic. These results suggest that bisulfite transformation of HEC may not occur by a mechanism involving mutation.
摘要
将叙利亚仓鼠胚胎细胞（HEC）在中性pH值下暴露于非致死、非诱变剂量的亚硫酸氢盐（SO2的生理形式）会导致转化呈剂量依赖性增加。当亚硫酸氢盐与紫外线照射联合使用时，转化诱导不具有协同性。这些结果表明，HEC的亚硫酸氢盐转化可能不是通过涉及突变的机制发生的。
Zotero 插件