Boeckx R L, Iosefsohn M, Hicks J M
Clin Chem. 1980 Apr;26(5):601-3.
We measured cerebrospinal fluid glutamine concentration in a reference group of 85 newborn to 30-month-old infants. All of the spinal taps were performed for the diagnosis of illnesses unrelated to hyperammonemia or hepatic encephalopathy. We also analyzed samples from patients with meningitis or cerebral hemorrhage, or who were receiving total parenteral nutrition. The mean glutamine concentration in cerebrospinal fluid in the reference group was somewhat lower than values reported for older children and adults. Values were significantly higher in patients with meningitis or cerebral hemorrhage and in those infants receiving total parenteral nutrition.
我们测量了85名年龄从新生儿到30个月大婴儿的参考组脑脊液谷氨酰胺浓度。所有腰椎穿刺均用于诊断与高氨血症或肝性脑病无关的疾病。我们还分析了患有脑膜炎或脑出血患者或接受全胃肠外营养患者的样本。参考组脑脊液中谷氨酰胺的平均浓度略低于年长儿童和成人报告的值。脑膜炎或脑出血患者以及接受全胃肠外营养的婴儿的值明显更高。
