Scheuer I, Rehn J
Unfallheilkunde. 1978 Nov;81(11):661-3.
Since April 1977 we have carried out more than 250 arthroscopies using a nitrous oxide insufflation device. Nitrous oxide is completely non-toxic to the tissues and is rapidly absorbed. Unlike carbon dioxide, which is the other commonly used insufflation gas, nitrous oxide does not combine with water to form an acid which can irritate the tissues. Furthermore, it is more rapidly absorbed than air. The normal insufflation pressure of 50 mm Hg is usually sufficient to expand the soft parts of the knee joint to the required degree. Interstitial nitrous oxide emphysema occurred in only 7 cases; it was of limited degree in each case and attributable to initial technical difficulties with the apparatus, selection of an excessive insufflation pressure, or additional stab incision. The nitrous oxide emphysema was always asymptomatic and, in some cases, was not even noticed by the patient. No infections of the knee joint or other serious complication followed insufflation with this device, which incorporated a bacterial filter.
自1977年4月以来,我们使用一氧化二氮充气装置进行了250多次关节镜检查。一氧化二氮对组织完全无毒且吸收迅速。与另一种常用的充气气体二氧化碳不同,一氧化二氮不与水结合形成会刺激组织的酸。此外,它比空气吸收得更快。50毫米汞柱的正常充气压力通常足以将膝关节的软组织扩张到所需程度。仅7例发生了间质性一氧化二氮气肿;在每种情况下程度都有限,且归因于设备最初的技术问题、选择过高的充气压力或额外的穿刺切口。一氧化二氮气肿始终无症状,在某些情况下患者甚至未注意到。使用带有细菌过滤器的该装置进行充气后,未发生膝关节感染或其他严重并发症。