Skrandies W
Int J Neurosci. 1981;14(1-2):77-84. doi: 10.3109/00207458108985818.
Visually evoked potentials to small patterned stimuli were recorded in an occipital row of five electrodes. The location of the flashed checkerboard stimuli of three different spatial frequencies varied in five steps from 5 degrees on the left to 5 degrees on the right hemiretina. Repeated recordings were obtained from seven healthy subjects and one Multiple Sclerosis patient. Stimulus location, electrode position and their interaction had stronger effects on the components derived from a principal components analysis than the spatial frequency. Components most significantly related to these spatial frequency or to an interaction between spatial frequency and other experimental conditions showed later peak latencies than those related to electrode position or stimulus location. This finding suggests a later or more sustained processing of pattern information. Discriminant analyses using the patient's component scores, separate principal components analysis, and the analysis of the patient's residual components all suggested major differences between the patient and the normals.
在枕叶的五个电极排成的行上记录了对小图案刺激的视觉诱发电位。三种不同空间频率的闪烁棋盘格刺激的位置在从左半视网膜5度到右半视网膜5度的范围内分五步变化。从7名健康受试者和1名多发性硬化症患者身上进行了重复记录。与空间频率相比，刺激位置、电极位置及其相互作用对主成分分析得出的成分有更强的影响。与这些空间频率或空间频率与其他实验条件之间的相互作用最显著相关的成分，其峰值潜伏期比与电极位置或刺激位置相关的成分更晚。这一发现表明对图案信息的处理更晚或更持续。使用患者的成分得分进行判别分析、单独的主成分分析以及对患者残余成分的分析均表明患者与正常人之间存在重大差异。
