Skrandies W, Lehmann D
Electroencephalogr Clin Neurophysiol. 1982 Dec;54(6):662-7. doi: 10.1016/0013-4694(82)90120-1.
Multichannel records of responses to large and small hemiretinal stimuli were obtained from 6 healthy subjects. Scalp distribution maps were constructed for all conditions at all post-stimulus times and component latencies were objectively determined by computing a reference-independent measure of field power. This procedure identified 2 components (at 100 and 140 msec). The scalp distribution data at these latencies were entered into a spatial principal components analysis which further reduced the data set to three underlying spatial principal components. These components may be regarded as reflecting underlying processes and were related to experimental conditions. A component reflecting lateralized brain activity displayed a significant interaction between size and retinal location of the stimulus with large stimuli showing a more pronounced lateralization over the hemisphere contralateral to the stimulated hemiretina, and the scores on this component were low for upper hemiretinal stimuli. These findings are in agreement with intracranially recorded evoked potential data and theoretical dipole source computations, and confirm a model of cortical neuronal generator processes whose locations and orientations in the hemisphere ipsilateral to the hemiretina stimulated are influenced not only by retinal stimulus location but also by stimulus size.
从6名健康受试者身上获取了对大、小半侧视网膜刺激的多通道反应记录。在所有刺激后时间点，针对所有条件构建头皮分布图，并通过计算场功率的参考独立测量值来客观确定成分潜伏期。该程序识别出2个成分（分别在100毫秒和140毫秒）。将这些潜伏期的头皮分布数据输入空间主成分分析，该分析进一步将数据集缩减为三个潜在的空间主成分。这些成分可被视为反映潜在过程，并与实验条件相关。一个反映大脑活动侧化的成分显示出刺激大小与视网膜位置之间存在显著交互作用，大刺激在与受刺激半侧视网膜对侧的半球上显示出更明显的侧化，而上半侧视网膜刺激在该成分上的得分较低。这些发现与颅内记录的诱发电位数据和理论偶极子源计算结果一致，并证实了一种皮质神经元发生器过程模型，其在受刺激半侧视网膜同侧半球中的位置和方向不仅受视网膜刺激位置影响，还受刺激大小影响。
