Ng W L
J Pathol. 1981 Jul;134(3):209-17. doi: 10.1002/path.1711340305.
By means of electron microscopy, three types of mesangial cell change were identified in IgA nephropathy. They represented proliferative, phagocytic and resting mesangial cells. The proliferative mesangial cells were characterised by the presence of centrioles, numerous free ribosomes, well developed Golgi apparatus and SER. They were found in the proliferative forms of IgA nephropathy. Phagocytic mesangial cells had numerous spinous cytoplasmic processes, better differentiated RER and numerous dense bodies and lipid inclusions. They were found in all histological forms of IgA nephropathy. The resting mesangial cells were unusual and were occasionally present in cases with normal numbers of mesangial cells.
通过电子显微镜检查，在IgA肾病中鉴定出三种类型的系膜细胞变化。它们分别代表增殖性、吞噬性和静止性系膜细胞。增殖性系膜细胞的特征是存在中心粒、大量游离核糖体、发育良好的高尔基体和滑面内质网。它们见于IgA肾病的增殖型。吞噬性系膜细胞有许多棘状细胞质突起、分化较好的粗面内质网以及大量致密体和脂质包涵体。它们见于IgA肾病的所有组织学类型。静止性系膜细胞较为少见，偶尔出现在系膜细胞数量正常的病例中。
