Griffis L C, Snipes M B, Brooks A L
J Toxicol Environ Health. 1981 Jan;7(1):117-24. doi: 10.1080/15287398109529963.
Fly ash from a fluidized-bed coal combustor was neutron-activated and administered to male Fischer 344 rats by a single nose-only inhalation exposure. The activated fly ash contained 46Sc and smaller amounts of other gamma-emitting radionuclides. Whole-body clearance of radioactivity to 127 d was described by an exponential equation, with the long-term component having a biological half-life of 78 d. High-resolution gamma spectra of the lungs were obtained with a Ge(Li) detector and the relative activities of several fly ash constituents were compared. The activities of 152Eu, 134Cs, 54Mn, and 60Co significantly decreased with time relative to those of 46Sc and 59Fe. These results indicate that the clearance of fly ash is similar to that of other relatively insoluble particles and that some elements may have been preferentially dissolved from the fly ash particles in vivo.
将流化床煤燃烧器产生的飞灰进行中子活化处理，通过单次仅经鼻吸入暴露的方式给予雄性Fischer 344大鼠。活化后的飞灰含有46Sc以及少量其他发射γ射线的放射性核素。放射性在127天内的全身清除情况用指数方程描述，长期成分的生物半衰期为78天。用锗锂探测器获得肺部的高分辨率γ能谱，并比较了几种飞灰成分的相对活度。相对于46Sc和59Fe，152Eu、134Cs、54Mn和60Co的活度随时间显著降低。这些结果表明，飞灰的清除情况与其他相对不溶性颗粒相似，并且某些元素可能已在体内从飞灰颗粒中优先溶解出来。
