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室温对大鼠繁殖、体重及器官重量、食物和水摄入量以及血液学的影响。

Effects of room temperature on reproduction, body and organ weights, food and water intake, and hematology in rats.

作者信息

Yamauchi C, Fujita S, Obara T, Ueda T

出版信息

Lab Anim Sci. 1981 Jun;31(3):251-8.

PMID:7265902
Abstract

Two generations of rats were raised at animal room temperature ranging from 12 to 32 degrees C at steps of 2 degrees C. The body weight of rats born in 22 degrees C environment and exposed to each temperature did not significantly differ within the range of 16-28 degrees C. The delivery rate, litter size, and weaning rate decreased at 30 degrees C and 32 degrees C, and only the weaning rate had a tendency to decrease at 12 degrees C. No significant difference was demonstrated within the 14-28 degrees C range for any reproduction parameter observed. The body weight of sucklings did not differ at birth within the 12-32 degrees C range; and at 3 weeks of age, there were no differences within the range of 18-28 degrees C. The body weight gain in both sexes after weaning was generally small when the temperature was below 18 degrees C or above 30 degrees C. There were no significant differences in food intake within the 20-26 degrees C range, in water intake within the 12-26 degrees C range, in hematological and serum biochemical values within the 20-26 degrees C range, and in organ weights within the 18-28 degrees C range. Therefore, the range of 20-26 degrees C (68-78 degrees F) was the optimum temperature range in rat rooms.

摘要

两代大鼠在12至32摄氏度、步长为2摄氏度的动物室温环境中饲养。在22摄氏度环境中出生并暴露于各温度下的大鼠,其体重在16至28摄氏度范围内无显著差异。在30摄氏度和32摄氏度时,分娩率、窝仔数和断奶率下降,在12摄氏度时只有断奶率有下降趋势。在所观察的任何繁殖参数方面,在14至28摄氏度范围内均未显示出显著差异。在12至32摄氏度范围内,仔鼠出生时体重无差异;在3周龄时,在18至28摄氏度范围内无差异。当温度低于18摄氏度或高于30摄氏度时,两性断奶后的体重增加通常较小。在20至26摄氏度范围内,食物摄入量无显著差异;在12至26摄氏度范围内,水摄入量无显著差异;在20至26摄氏度范围内,血液学和血清生化值无显著差异;在18至28摄氏度范围内,器官重量无显著差异。因此,20至26摄氏度(68至78华氏度)是大鼠饲养室的最佳温度范围。

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