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[地塞米松对实验性失血性休克心肌超微结构的影响]

[Effect of dexamethasone on the ultrastructure of the myocardium in experimental hemorrhagic shock].

作者信息

Sátori O, Balogh I, Rubányi G, Kovách A

出版信息

Morphol Igazsagugyi Orv Sz. 1980 Apr;20(2):94-7.

PMID:7266508
Abstract

Authors studied the ultrastructure of the myocardium of rats treated with Dexamethasone in experimental haemorrhagic shock of 2.5 hours duration. The perfusion was performed on the Langendorff cannula. After preliminary treatment with Dexamethasone no characteristic morphological picture of the shock developed, but a marked accumulation of glycogen was observed. Authors believe that morphological pictures unambiguously evidence the anti-shock effect of Dexamethasone.

摘要

作者研究了在持续2.5小时的实验性失血性休克中接受地塞米松治疗的大鼠心肌超微结构。在Langendorff插管上进行灌注。用地塞米松预处理后,未出现休克的特征性形态学表现,但观察到糖原显著积聚。作者认为,形态学表现明确证明了地塞米松的抗休克作用。

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