Várbiró M, Burger T, Minik K, István L
Morphol Igazsagugyi Orv Sz. 1981 Jan;21(1):1-8.
In 10 cases of hairy cell leukaemia histological, cytological, cytochemical and in some of the cases immunocytological investigations were carried out. In addition to clinical, cytological and cytochemical findings arising suspicion of hairy cell leukaemia, in three cases the multifocal reaction of acid-phosphatase appeared to be tartarate sensitive (at the concentration of L+-tartaric acid--0,75%), indicating in accordance with findings of Burns et al. (9), that tartarate resistency of the acid-phosphatase reaction ("isoenzyme 5" Katayama és mtsai, 24) has no absolute diagnostic significance. Pathomorphological investigation of different tissues (spleen, lymph node, bone marrow, liver) has revealed the characteristic localization of the spleen infiltrates (cords of Billroth) and the formation of the so called pseudosinuses. These morphological findings may contribute to the diagnosis of hairy cell leukaemia.
对10例毛细胞白血病患者进行了组织学、细胞学、细胞化学检查，部分病例还进行了免疫细胞学检查。除了临床、细胞学和细胞化学检查结果引发对毛细胞白血病的怀疑外，在3例病例中，酸性磷酸酶的多灶性反应似乎对酒石酸盐敏感（L + -酒石酸浓度为0.75%），这与伯恩斯等人（9）的研究结果一致，表明酸性磷酸酶反应的酒石酸盐抗性（“同工酶5”，片山和蔡，24）没有绝对的诊断意义。对不同组织（脾脏、淋巴结、骨髓、肝脏）的病理形态学研究揭示了脾脏浸润（毕罗氏索）的特征性定位以及所谓假血窦的形成。这些形态学发现可能有助于毛细胞白血病的诊断。
