Kovács M, Barna M
Morphol Igazsagugyi Orv Sz. 1981 Apr;21(2):142-9.
At 42 children with malabsorption syndrome 65 peroral intestinal biopsies have been taken. In 7 cases three consecutive biopsies - at the onset of symptoms (1.), after gluten withdrawal (2.) and after reintroduction of gluten (3.) - were obtained. In 3 cases two biopsies, the (2.) and the (3.) were examined. On the basis of the clinico-morphological analysis of 27 biopsies gluten sensitive enteropathy was diagnosed in 6 cases. In 4 cases the reaction of the intestinal mucosa on withdrawal and reintroduction of gluten indicated transient gluten intolerance. As an effect of the dietary treatment introduced according to the morphological alterations of intestinal mucosa normal development of children started. Authors believe that the diagnosis of the gluten sensitive enteropathy and it's differentiation from the transient gluten intolerance should be based on the morphological examination of the intestinal mucosa.
对42例吸收不良综合征患儿进行了65次经口肠道活检。7例患者在症状出现时（1.）、停用麸质后（2.）和重新引入麸质后（3.）获得了连续三次活检。3例患者检查了两次活检，即（2.）和（3.）。根据对27次活检的临床形态学分析，6例诊断为麸质敏感性肠病。4例患者肠道黏膜对停用和重新引入麸质的反应表明存在短暂的麸质不耐受。根据肠道黏膜的形态学改变进行饮食治疗后，儿童开始正常发育。作者认为，麸质敏感性肠病的诊断及其与短暂性麸质不耐受的鉴别应基于肠道黏膜的形态学检查。
