Bracher M, Swistak J, Noser F
Mutat Res. 1981 Jul-Sep;91(4-5):363-9. doi: 10.1016/0165-7992(81)90016-6.
The hair-dye component resorcinol was tested for potential in vivo induction of sister-chromatid exchanges (SCE) in bone-marrow cells after intraperitoneal, peroral and epicutaneous application to rats. None of the tested drug concentrations produced an increase in SCE frequencies. As a control for our test method we demonstrated dose-dependent SCE increases induced by 2-acetylaminofluorene and by 2-aminoanthracene, cytogenetic response to 2-aminoanthracene being higher in females than in males.
将染发剂成分间苯二酚经腹腔内、经口和经皮给药大鼠后，测试其在体内诱导骨髓细胞姐妹染色单体交换（SCE）的可能性。所测试的任何药物浓度均未使SCE频率增加。作为我们测试方法的对照，我们证明了2-乙酰氨基芴和2-氨基蒽可诱导剂量依赖性SCE增加，雌性对2-氨基蒽的细胞遗传学反应高于雄性。
