A rapid and sensitive enzymatic-isotopic method for routine assay of histamine in blood, plasma and biopsy tissue: re-evaluation.

The enzymatic-isotopic method for determination of histamine has been reevaluated. Modifications, permitting routine analysis of the amine in blood, plasma and biopsy tissues of various origin have been described; this permits convenient application of the technique in various fields of clinical pharmacology, gastroenterology and immunology.