Duke E M, Hussein D M, Hamilton W
Scott Med J. 1981 Jul;26(3):240-4. doi: 10.1177/003693308102600309.
11 out of the 13 children with Turner's syndrome currently attending our endocrine clinic were investigated for possible growth hormone deficiency. The parents of two of the 13 children refused permission for these studies. One child had inadequate hypoglycaemia and the test was not repeated. Six of the ten children with adequate hypoglycaemia had an adequate growth hormone response to hypoglycaemia, while 4 children did not. This contradicts several previous studies on children with Turner's syndrome, which have reported normal growth hormone responses to provocative tests. In the normal population approximately one in 15 has an inadequate growth hormone response to hypoglycaemia.
目前在我们内分泌诊所就诊的13名特纳综合征患儿中,有11名接受了生长激素缺乏症的相关检查。13名患儿中有2名的家长拒绝同意进行这些检查。有一名患儿低血糖反应不充分,未重复进行该项检查。在低血糖反应充分的10名患儿中,有6名对低血糖有充分的生长激素反应,而另外4名患儿则没有。这与之前几项关于特纳综合征患儿的研究结果相矛盾,那些研究报告称患儿对激发试验有正常的生长激素反应。在正常人群中,约每15人中就有1人对低血糖的生长激素反应不充分。