Brasher C, Siegler R L
West J Med. 1981 Mar;134(3):193-7.
Our experience with 61 episodes of the hemolytic-uremic syndrome in 60 patients showed a mean patient age of 3 years and a higher incidence of the disease during the summer months. Diarrhea, often bloody, preceded the other features of the illness in 93 percent of the cases. Hemolytic anemia, hematuria and proteinuria occurred in all of the patients. Thrombocytopenia and severe azotemia (blood urea nitrogen greater than 100 mg per dl) occurred in 74 percent and 72 percent of the children, respectively. Blood transfusions were necessary in 64 percent and dialysis was required in 54 percent of the cases. Mortality was low (5 percent) and 85 percent of the children had a complete recovery.
我们对60例患者的61次溶血尿毒综合征发作的经验表明,患者平均年龄为3岁,且该疾病在夏季发病率较高。在93%的病例中,腹泻(通常为血性)先于疾病的其他特征出现。所有患者均出现溶血性贫血、血尿和蛋白尿。74%的儿童出现血小板减少症,72%的儿童出现严重氮质血症(血尿素氮大于100mg/dl)。64%的病例需要输血,54%的病例需要透析。死亡率较低(5%),85%的儿童完全康复。