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[中缝核在小猫体感皮层神经元活动发育中的作用]

[Role of raphe nuceli in the development of somatosensory cortex neuronal activity in the kitten].

作者信息

Raevskiĭ V V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1981;31(2):349-57.

PMID:7269785
Abstract

The formation of background and evoked unit activity in the I somatosensory cortical zone was traced in acute experiments on 5 to 20 days old kittens. Stimulation of anterior (median, dorsal) raphe nuclei inhibits the spike activity of cortical units in kittens beginning with the age of 11 to 12 days and modulates evoked responses. This is manifested in the transformation of immature tonic reactions into phasic, which are inherent in a more definitive type of reaction. The role of the serotoninergic mechanisms in the formation of recurrent inhibition in the cortex is discussed, as well as heterochroneous formation of monoaminergic brain systems in the process of postnatal development.

摘要

在对5至20日龄小猫进行的急性实验中,追踪了躯体感觉皮层I区背景活动和诱发单位活动的形成。刺激中缝前核(中缝正中核、中缝背核)可抑制11至12日龄开始的小猫皮层单位的锋电位活动,并调节诱发反应。这表现为将不成熟的强直反应转变为更具确定性反应类型所固有的相位反应。文中讨论了血清素能机制在皮层反馈抑制形成中的作用,以及单胺能脑系统在出生后发育过程中的异时形成。

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