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γ辐射对大鼠组织弹性蛋白含量及血清弹性蛋白酶活性的影响。

Effect of gamma radiation on tissue elastin content and serum elastolytic activity in rats.

作者信息

Drózdz M, Olczyk K, Piwowarczyk B, Stawiarska B

出版信息

Acta Physiol Pol. 1981 Mar-Apr;32(2):187-92.

PMID:7270219
Abstract

The elastin content of aorta, heart, skin and lungs as well as the serum elastolytic activity were determined in rats exposed to radiation. It was found that a single irradiation of rats with gamma rays (500 r) caused a decrease of the elastin content in all examined tissues. The serum elastolytic activity in the irradiated rats was increased. It is suggested that elastin degradation following radiation may be caused by changes in its molecular structure and possibly, due to increased serum elastolytic activity.

摘要

测定了受辐射大鼠的主动脉、心脏、皮肤和肺的弹性蛋白含量以及血清弹性蛋白酶活性。发现用γ射线单次照射大鼠(500伦琴)会导致所有检测组织中的弹性蛋白含量降低。受辐射大鼠的血清弹性蛋白酶活性增加。提示辐射后弹性蛋白降解可能是由于其分子结构变化,也可能是由于血清弹性蛋白酶活性增加所致。

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