Kirklin J K, Blackstone E H, Kirklin J W, McKay R, Pacifico A D, Bargeron L M
Am J Cardiol. 1981 Sep;48(3):507-12. doi: 10.1016/0002-9149(81)90080-1.
Data are reported on 142 infants less than 3 months old who left the operating room alive after an open intracardiac operation during the 13 years from January 1967 to July 1980. The probability of postoperative in-hospital cardiac death for acute postoperative heart failure (the most common mode of death in these infants) was found by multivariate logistic analysis to be significantly related only to the strength of pedal pulses, the pedal skin temperature and the cardiac index in the first 5 postoperative hours. When cardiac index was not analyzed and cold cardioplegic myocardial preservation methods used, only pedal pulses and pedal skin temperature were significant predictors of hospital death. Blood pressure and heart rate were not related to this mode of hospital death. Oliguria occurred in 23 percent of patients; it was related primarily to inadequate cardiac performance and increased the probability of hospital death. Treatment protocols are derived based on these facts.
报告了1967年1月至1980年7月这13年间,142例3个月以下婴儿在心脏直视手术后存活离开手术室的情况。通过多因素逻辑分析发现,术后急性心力衰竭(这些婴儿最常见的死亡方式)导致的院内心脏死亡概率仅与术后最初5小时的足背动脉搏动强度、足背皮肤温度和心脏指数显著相关。当不分析心脏指数且采用冷停跳液心肌保护方法时,只有足背动脉搏动和足背皮肤温度是院内死亡的显著预测因素。血压和心率与这种院内死亡方式无关。23%的患者出现少尿;这主要与心功能不全有关,并增加了院内死亡的概率。基于这些事实制定了治疗方案。