Fantl J A, Hurt W G, Dunn L J
Am J Obstet Gynecol. 1981 Aug 15;140(8):885-90. doi: 10.1016/0002-9378(81)90079-x.
Ninety-two (24.6%) of 374 patients referred to our gynecologic urology unit were found to have instability of the detrusor muscle with no recognizable associated pathologic conditions: idiopathic detrusor instability. Thirty-nine (42.4%) of these 92 patients demonstrated the instability only after detrusor activation maneuvers such as coughing, heel bouncing, or positional changes. The cure rate among patients with both "spontaneous" and "provoked" contractions of the detrusor muscle was comparable to the cure rate among those whose bladder contractions were apparent only after detrusor activation maneuvers (p greater than 0.9). The success rate of bladder retraining drills (BRD) as the sole mode of therapy was not significantly different from that observed with BRD combined with anticholinergics (p greater than 0.6).
在转诊至我们妇科泌尿科的374名患者中,有92名(24.6%)被发现存在逼尿肌不稳定,且无明显相关病理状况:特发性逼尿肌不稳定。这92名患者中有39名(42.4%)仅在进行咳嗽、足跟跳动或体位改变等逼尿肌激活动作后才表现出不稳定。逼尿肌出现“自发性”和“诱发性”收缩的患者的治愈率与那些仅在逼尿肌激活动作后膀胱收缩才明显的患者的治愈率相当(p大于0.9)。膀胱再训练练习(BRD)作为唯一治疗方式的成功率与BRD联合抗胆碱能药物时观察到的成功率无显著差异(p大于0.6)。