Koopmann C F, Feld R A, Coulthard S W
Am J Otolaryngol. 1981 May;2(2):123-8. doi: 10.1016/s0196-0709(81)80029-4.
Until recent years cricothyroidotomy has been condemned as an elective surgical procedure because of reports of a high incidence of subglottic stenosis. In this study of cricothyroidotomy the effects of trauma, denudation of the mucous membrane of the anterior half of the cricoid cartilage, and the prophylactic administration of antibiotics (ampicillin) on the development of subglotttic airway narrowing were evaluated in 40 mongrel dogs. Two of the dogs developed minimal anterior narrowing of the airway. None of the dogs developed clinically important stenosis.
直到近年来，由于有报告称声门下狭窄的发生率很高，环甲膜切开术一直被视为一种非选择性外科手术。在这项关于环甲膜切开术的研究中，对40只杂种犬评估了创伤、环状软骨前半部分黏膜剥脱以及预防性使用抗生素（氨苄青霉素）对声门下气道狭窄发展的影响。其中两只犬出现了轻微的气道前部狭窄。没有一只犬出现具有临床意义的狭窄。
