Keith I, Shenoy B J
Anaesthesia. 1981 Jul;36(7):702-4. doi: 10.1111/j.1365-2044.1981.tb08786.x.
In 38 patients subjected to minor surgery, totally intravenous anaesthesia with low dose ketamine and Althesin produced adequate operating conditions in 92% of patients with minimal cardiorespiratory disturbance. Problems arose from muscular hypertonus, spontaneous movement and occasionally salivation. Initial recovery was quicker and the incidence of side-effects lower, than those reported when ketamine was used as the sole agent. The technique could be useful in difficult situations as an alternative to inhalation anaesthesia or other intravenous techniques.
在38例接受小手术的患者中，采用低剂量氯胺酮和阿法沙龙进行全静脉麻醉，92%的患者获得了足够的手术条件，且心肺功能干扰最小。问题出在肌肉张力亢进、自主运动以及偶尔出现的流涎。与单独使用氯胺酮时的报道相比，初始恢复更快，副作用发生率更低。该技术在困难情况下可作为吸入麻醉或其他静脉麻醉技术的替代方法。
