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1
Halothane sensitivity, the H blood group system and phosphohexose isomerase (PHI) in pigs. A linkage study of physiological importance.猪的氟烷敏感性、H血型系统与磷酸己糖异构酶（PHI）。一项具有生理重要性的连锁研究。
Acta Vet Scand. 1978;19(3):458-60. doi: 10.1186/BF03547614.
2
Halothane sensitivity and linkage of genes for H red blood cell antigens, phosphohexose isomerase (PHI) and 6-phosphogluconate dehydrogenase (6-PGD) variants in pigs.猪中氟烷敏感性以及H红细胞抗原、磷酸己糖异构酶（PHI）和6 - 磷酸葡萄糖酸脱氢酶（6 - PGD）变体基因的连锁关系
Anim Blood Groups Biochem Genet. 1980;11(2):93-107. doi: 10.1111/j.1365-2052.1980.tb01499.x.
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Linkage of genes for PHI, halothane sensitivity, A-O inhibition, H red blood cell antigens and 6-PGD variants in pigs.猪中PHI、氟烷敏感性、A-O抑制、H红细胞抗原和6-磷酸葡萄糖脱氢酶变体的基因连锁
Anim Blood Groups Biochem Genet. 1981;12(3):207-9. doi: 10.1111/j.1365-2052.1981.tb01552.x.
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Linkage studies between the halothane (Hal), phosphohexose isomerase (Phi) and the S(A-O) and H red blood cell loci of Pietrain/Hampshire and Landrace pigs.皮特兰/汉普夏猪和长白猪中氟烷（Hal）、磷酸己糖异构酶（Phi）与红细胞S(A - O)和H位点之间的连锁研究。
Anim Blood Groups Biochem Genet. 1982;13(4):245-62. doi: 10.1111/j.1365-2052.1982.tb01568.x.
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Gene order and recombination rates in the linkage group S-Phi-Hal-H-(Po2)-Pgd in pigs.猪的连锁群S-Phi-Hal-H-(Po2)-Pgd中的基因顺序和重组率
Anim Blood Groups Biochem Genet. 1985;16(4):307-18. doi: 10.1111/j.1365-2052.1985.tb01482.x.
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The position of the epistatic S locus in the halothane linkage group in pigs.
Anim Blood Groups Biochem Genet. 1985;16(4):297-305. doi: 10.1111/j.1365-2052.1985.tb01481.x.
7
[Genetic relationship of the loci of phosphohexose isomerase and G-system blood groups in swine].
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Relationships between the H and A-O blood types, phosphohexose isomerase and 6-phosphogluconate dehydrogenase red cell enzyme systems and halothane sensitivity, and economic traits in a superior and an inferior selection line of swiss landrace pigs.
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9
[The "hitch-hiking" effect of a selected gene and gamete combination (linkage disequilibrium): the example of 2 closely linked loci in the swine, Hal (halothane sensitivity) and PHI (phosphohexose isomerase)].
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10
Close linkage established between the HAL locus for halothane sensitivity and the PHI (phosphohexose isomerase) locus in pigs of the Danish Landrace breed.在丹麦长白猪品种中，建立了氟烷敏感性的HAL基因座与PHI（磷酸己糖异构酶）基因座之间的紧密连锁关系。
Nord Vet Med. 1977 Nov;29(11):502-4.

本文引用的文献

1
Sequential tests for the detection of linkage.用于检测连锁的序贯检验。
Am J Hum Genet. 1955 Sep;7(3):277-318.
2
H blood types in pigs as predictors of stress susceptibility.猪的H血型作为应激易感性的预测指标。
Science. 1976 Mar 5;191(4230):947-8. doi: 10.1126/science.1251204.
3
Phosphohexose isomerase (PHI) and porcine halothane sensitivity.磷酸己糖异构酶（PHI）与猪的氟烷敏感性
Acta Vet Scand. 1976;17(3):370-2. doi: 10.1186/BF03547918.
4
Close linkage established between the HAL locus for halothane sensitivity and the PHI (phosphohexose isomerase) locus in pigs of the Danish Landrace breed.在丹麦长白猪品种中，建立了氟烷敏感性的HAL基因座与PHI（磷酸己糖异构酶）基因座之间的紧密连锁关系。
Nord Vet Med. 1977 Nov;29(11):502-4.

猪的氟烷敏感性、H血型系统与磷酸己糖异构酶（PHI）。一项具有生理重要性的连锁研究。

Halothane sensitivity, the H blood group system and phosphohexose isomerase (PHI) in pigs. A linkage study of physiological importance.

作者信息

Jørgensen Preben Fogd

出版信息

Acta Vet Scand. 1978;19(3):458-60. doi: 10.1186/BF03547614.

DOI:10.1186/BF03547614
PMID:727087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8366360/
Abstract

Previous investigations have clearly shown the existence of associations between halothane sensitivity, the H blood group system and the PHI enzyme system in pigs ( 1976, 1976). These associations which have considerable practical interest are most probably linkage phenomenons ( 1977, 1977). The major recessive locus for halothane sensitivity (HAL) comprises the two alleles N and n, n being responsible for halothane sensitivity. The distances between this locus and the loci for H and PHI are still not known exactly. This communication aims at clarifying these problems.

摘要

先前的研究已清楚表明猪的氟烷敏感性、H血型系统和PHI酶系统之间存在关联（1976年，1976年）。这些具有重大实际意义的关联很可能是连锁现象（1977年，1977年）。氟烷敏感性的主要隐性基因座（HAL）包含两个等位基因N和n，n导致氟烷敏感性。该基因座与H和PHI基因座之间的距离仍不完全清楚。本通讯旨在阐明这些问题。