猪的氟烷敏感性、H血型系统与磷酸己糖异构酶（PHI）。一项具有生理重要性的连锁研究。

Halothane sensitivity, the H blood group system and phosphohexose isomerase (PHI) in pigs. A linkage study of physiological importance.

作者信息

Jørgensen Preben Fogd

出版信息

Acta Vet Scand. 1978;19(3):458-60. doi: 10.1186/BF03547614.

DOI:10.1186/BF03547614

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8366360/

Abstract

Previous investigations have clearly shown the existence of associations between halothane sensitivity, the H blood group system and the PHI enzyme system in pigs ( 1976, 1976). These associations which have considerable practical interest are most probably linkage phenomenons ( 1977, 1977). The major recessive locus for halothane sensitivity (HAL) comprises the two alleles N and n, n being responsible for halothane sensitivity. The distances between this locus and the loci for H and PHI are still not known exactly. This communication aims at clarifying these problems.

摘要

先前的研究已清楚表明猪的氟烷敏感性、H血型系统和PHI酶系统之间存在关联（1976年，1976年）。这些具有重大实际意义的关联很可能是连锁现象（1977年，1977年）。氟烷敏感性的主要隐性基因座（HAL）包含两个等位基因N和n，n导致氟烷敏感性。该基因座与H和PHI基因座之间的距离仍不完全清楚。本通讯旨在阐明这些问题。

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Halothane sensitivity, the H blood group system and phosphohexose isomerase (PHI) in pigs. A linkage study of physiological importance.猪的氟烷敏感性、H血型系统与磷酸己糖异构酶（PHI）。一项具有生理重要性的连锁研究。

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[The "hitch-hiking" effect of a selected gene and gamete combination (linkage disequilibrium): the example of 2 closely linked loci in the swine, Hal (halothane sensitivity) and PHI (phosphohexose isomerase)].

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Close linkage established between the HAL locus for halothane sensitivity and the PHI (phosphohexose isomerase) locus in pigs of the Danish Landrace breed.在丹麦长白猪品种中，建立了氟烷敏感性的HAL基因座与PHI（磷酸己糖异构酶）基因座之间的紧密连锁关系。

Nord Vet Med. 1977 Nov;29(11):502-4.

本文引用的文献

1

Sequential tests for the detection of linkage.用于检测连锁的序贯检验。

Am J Hum Genet. 1955 Sep;7(3):277-318.

2

H blood types in pigs as predictors of stress susceptibility.猪的H血型作为应激易感性的预测指标。

Science. 1976 Mar 5;191(4230):947-8. doi: 10.1126/science.1251204.

3

Phosphohexose isomerase (PHI) and porcine halothane sensitivity.磷酸己糖异构酶（PHI）与猪的氟烷敏感性

Acta Vet Scand. 1976;17(3):370-2. doi: 10.1186/BF03547918.

4

Close linkage established between the HAL locus for halothane sensitivity and the PHI (phosphohexose isomerase) locus in pigs of the Danish Landrace breed.在丹麦长白猪品种中，建立了氟烷敏感性的HAL基因座与PHI（磷酸己糖异构酶）基因座之间的紧密连锁关系。

Nord Vet Med. 1977 Nov;29(11):502-4.

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