Marín J, Lasa R, Olcoz M, Echeveste A, García J, Albisu Y, Guerrero R, Ochoa de Olza M, Barbarín I, Jiménez de Retana J
An Esp Pediatr. 1981 Mar;14(3):168-74.
Authors report six cases on Burkitt's lymphoma seen during the last 18 months. In all of them a large ileocecal tumor was present and five of them had a bone marrow involvement. The ascitic fluid was positive in all cases. Three of the patients had a marked jaundice at diagnosis. The immunologic markers study on two of the cases, made evident that they belonged to type B. One of these two cases showed a component M in serum of the IgM type. As soon as chemotherapy started two of the cases showed marked metabolic disturbances. Three of the cases died and the three others remain free of disease for as long as two, 26 and 21 months. This report arises a comment epidemiologic importance of the increased frequency of Burkitt's lymphoma during the last months, as well as the clinic features of the six reported cases as compared to series published in non endemic areas on this topic.
作者报告了过去18个月中所见的6例伯基特淋巴瘤病例。所有病例均存在巨大的回盲部肿瘤，其中5例有骨髓受累。所有病例的腹水均呈阳性。3例患者在诊断时出现明显黄疸。对其中2例病例进行的免疫标志物研究表明，它们属于B型。这2例病例中的1例血清中显示有IgM型的M成分。化疗一开始，其中2例病例就出现了明显的代谢紊乱。3例病例死亡，另外3例在长达2、26和21个月的时间里无疾病复发。本报告引发了关于过去几个月伯基特淋巴瘤发病率增加的流行病学重要性的讨论，以及与非流行地区关于该主题发表的系列病例相比，这6例报告病例的临床特征。
