Charmot G, Rodhain F, Roze J M
Nouv Presse Med. 1978 Jan 28;7(4):277-9.
Epidemiology of tropical Burkitt's lymphoma shows the concomitant existence of the three following characteristics in endemic areas: - fairly dense rural population with a low standard of living; - early occurrence of primary infection by the Epstein-Barr virus (whose genome is always present in all tumour cells); - stable malaria. The social and economic level of these areas accounts for the specific features of the viral infection. Climatic factors determine permanent of prolonged transmission of malaria which could be mediated through a mitogen. Eradication of malaria could be a useful way to induce a fall in Burkitt's lymphoma incidence.
热带伯基特淋巴瘤的流行病学研究表明，在流行地区同时存在以下三个特征：- 农村人口密度较大且生活水平较低；- 早期感染爱泼斯坦-巴尔病毒（其基因组始终存在于所有肿瘤细胞中）；- 疟疾流行稳定。这些地区的社会经济水平决定了病毒感染的具体特征。气候因素决定了疟疾的长期持续传播，这可能是由一种促有丝分裂原介导的。根除疟疾可能是降低伯基特淋巴瘤发病率的有效方法。
