Goodsaid-Zalduondo F, Engelman D M
Biophys J. 1981 Sep;35(3):587-94. doi: 10.1016/S0006-3495(81)84814-X.
The conformations of liquid n-alkanes have been studied using neutron scattering techniques to better understand the conformational forces present in membrane lipid interiors. We have studied hydrocarbon chains having lengths comparable to those found for esterified membrane lipid fatty acids, and find that the steric constraints of packing in the liquid state do not change the conformational distributions of hydrocarbon chains from those imposed by the intrachain forces present in the gas phase. It follows that the central region of membranes containing lipids in the disordered state should contain hydrocarbon chain conformations determined primarily by intrachain forces.
已使用中子散射技术研究了液态正构烷烃的构象，以便更好地理解膜脂内部存在的构象力。我们研究了长度与酯化膜脂脂肪酸相当的烃链，发现液态堆积的空间位阻约束并不会改变烃链的构象分布，使其与气相中链内作用力所施加的构象分布不同。由此可见，含有处于无序状态脂质的膜的中心区域应包含主要由链内作用力决定的烃链构象。
