Jacobs R M, Valli V E, Wilkie B N
Can J Comp Med. 1981 Jan;45(1):82-6.
The detection of circulating soluble tumor-associated antigen by radioimmunoassay was attempted in cows with lymphoma. The assay system did detect PAGE-purified tumor-associated antigen but did not detect immunoreactive substances in the sera of 20 affected animals and 20 normal cattle. Similarly, ultrafiltration of low pH-dissociated serum to separate immune complexes did not aid in the detection of antigen.
尝试采用放射免疫分析法检测患淋巴瘤奶牛体内循环的可溶性肿瘤相关抗原。该检测系统确实能检测到经聚丙烯酰胺凝胶电泳（PAGE）纯化的肿瘤相关抗原，但在20头患病动物和20头正常牛的血清中未检测到免疫反应性物质。同样，对低pH解离血清进行超滤以分离免疫复合物，也无助于抗原的检测。
