Kawai T, Takanashi H, Nakayama M, Mori H, Hirono I
Cancer Lett. 1981 Mar;12(1-2):29-35. doi: 10.1016/0304-3835(81)90034-3.
Effect of storage on carcinogenic activity of bracken fern was examined with inbred strain ACI rats of both sexes. The experiment was broken down into 3 groupings: Group I received a diet containing fresh dry bracken powder: Group II received a diet which contained the same dry bracken powder used in Group I but preserved for 1 year at 4 degrees C (Group II-C) or room temperature (Group II-R); Group III received the diet containing bracken powder preserved for 2 years at 4 degrees C (Group III-C) or room temperature (Group III-R). Three control groups corresponding to Groups I, II and III were fed a normal basal diet. Significant differences in incidence of ileal tumors were observed between Group I and both groups of Group III and latent period of intestinal tumors in Group II or III was longer than that of Group I. The results indicate a decreased carcinogenic activity of bracken fern by preservation.
