Malendowicz L K, Majchrzak M
Endokrinologie. 1981 Jul;77(3):297-302.
At weekly intervals between 21 and 84 days of postnatal ontogenesis, on the thyroid glands of male and female rats morphometric studies were performed. The rate of body growth was similar in male and female rats between 21 and 42 days. Thereafter male rats are heavier than females. There were no differences in composition of particular histologic components studied in the thyroids of male and female rats between 21 and 35 days. From day 42 the volume fraction of colloid is lower in the male than female gland. Also from day 49 of postnatal ontogenesis the follicular cells are taller in male than in female thyroid gland. After reaching puberty in the female thyroid gland a gradual lowering of the volume fraction of epithelium and an increase in volume fraction of colloid are observed. Due to these changes epithelium/colloid ratio in female rats markedly declines between 42 and 84 days of postnatal ontogenesis while in the male rats this ratio is higher and does not show such a distinct decline.
在出生后发育的21至84天期间，每隔一周对雄性和雌性大鼠的甲状腺进行形态计量学研究。21至42天期间，雄性和雌性大鼠的身体生长速度相似。此后，雄性大鼠比雌性大鼠更重。在21至35天期间，对雄性和雌性大鼠甲状腺中特定组织学成分的组成进行研究，未发现差异。从42天起，雄性腺体中胶体的体积分数低于雌性。同样，从出生后发育的49天起，雄性甲状腺中的滤泡细胞比雌性甲状腺中的更高。雌性甲状腺在达到青春期后，观察到上皮细胞体积分数逐渐降低，胶体体积分数增加。由于这些变化，雌性大鼠在出生后发育的42至84天期间上皮细胞/胶体的比例显著下降，而雄性大鼠的这一比例更高，且没有如此明显的下降。
