Mascaró J M, Ferrando J, Palou J, Bombí J A
Dermatologica. 1981;163(1):52-7. doi: 10.1159/000250140.
Optical microscopical studies were carried out on biopsies from 22 patients affected by saburral tongue (ST). The histopathological pattern consisted of a papillomatous acanthosis covered with a very thick horny layer. Abundant colonies of banal germs were seen in the keratin. There was an alternation of suprapapillary orthokeratosis and interpapillary parakeratosis. Under the keratin layer all the keratinocytes were large and clear with a glycogen-filled cytoplasm. Two specimens, studied with a transmission electron microscope, only showed that the keratinocytes were filled with glycogen. The clear glycogen-filled epithelial cells are common either in normal lingual epithelium or in some pathological conditions. The microscopic field of ST is quite similar to that of the hairy black tongue; but these peculiar clinical aspects of the tongue do not evolve one through the other.
对22例患毛舌的患者活检组织进行了光学显微镜研究。组织病理学模式表现为乳头瘤样棘皮症，其上覆盖着一层非常厚的角质层。在角质层中可见大量普通菌菌落。乳头上方正角化和乳头间角化不全交替出现。在角质层下，所有角质形成细胞都很大且清晰，细胞质充满糖原。用透射电子显微镜研究的两个标本仅显示角质形成细胞充满糖原。充满糖原的透明上皮细胞在正常舌上皮或某些病理状况中都很常见。毛舌的显微镜视野与黑毛舌非常相似；但舌头的这些特殊临床特征并不会相互演变。
