Adverse reactions in connection with albumin and other plasma substitutes.

The side effects after the infusion of human albumin solutions, stabilized human serum and a modified gelatin are analysed. Diseases and indications for the application are listed. Intervals between application and side effects as well as frequency and type of symptoms are shown. Different symptoms and intervals allow the conclusion that different pathomechanism are responsible for the adverse reactions. Due to a steady improvement in production and control the number of reported adverse reactions shows a steady decrease.