Aldor E, Heeger H
Herz. 1980 Aug;5(4):251-6.
An analysis of left ventricular angiograms not seldom revealed a diastolic mitral regurgitation. There was neither a correlation between the diastolic mitral regurgitation and the anatomic situation in the coronary system nor with the left ventricular function. The diastolic regurgitation always occurred in a postextrasystolic pause at the end of the diastole. While the systolic mitral regurgitation produces a jet appearance of contrast material, the diastolic mitral regurgitation is seen as a floating of contrast material into the atrium. The cause of the diastolic mitral regurgitation appears to be an incremented left ventricular filling subsequent to repeated and incoordinately-occurring extrasystoles with diminished systolic ejection which leads to reversal of the pressure gradient between the left atrium and left ventricle and permits regurgitation over the incompletely closed valve.
对左心室血管造影的分析常常显示存在舒张期二尖瓣反流。舒张期二尖瓣反流与冠状动脉系统的解剖情况以及左心室功能之间均无关联。舒张期反流总是发生在舒张期末期的早搏后间歇期。收缩期二尖瓣反流会使造影剂呈现喷射状，而舒张期二尖瓣反流则表现为造影剂漂浮至心房。舒张期二尖瓣反流的原因似乎是反复且不协调出现的早搏后，左心室充盈增加，同时收缩期射血减少，这导致左心房与左心室之间的压力梯度逆转，使得造影剂能够通过未完全关闭的瓣膜发生反流。
