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儿童不明原因发热(作者译)

[Fever of unknown origin in children (author's transl)].

作者信息

Cruz Guerrero G, Navarro González J, Cintado Bueno C

出版信息

An Esp Pediatr. 1978 Oct;11(10):683-92.

PMID:727602
Abstract

A study has been made of 79 children from zero to seven years of age admitted to hospital with fever of unknown origin (F.U.O.) of more than two weeks duration. Children in whom fever was not clinically observed after one week of hospitalization are not included. In 50 cases (63.2%), it was possible to establish a definitive diagnosis within the first fornight of admission. The most frequent cause of fever was that of infection, found in 51 children (64.5%), tuberculosis and urinary infections predominating with ten cases each. In another ten children neoplastic disease was diagnosed (mostly leucosis), and there was colagenosis in seven cases (8.8%). In another seven children, the etiology was not established. Mortality rate was 7.5%. Clinical history and exploration were of main importance in the orientation of the diagnoses. The findings of this study suggest that in all children presenting F.U.O., apart from hospitalization of at least one week, a very thorough anamnesis and clinical exploration are most important in establishing the diagnosis, along with a more or less aggressive approach to the problem according to the findings.

摘要

对79名年龄在0至7岁因持续两周以上不明原因发热(F.U.O.)而住院的儿童进行了一项研究。住院一周后未观察到临床发热的儿童未纳入研究。在50例(63.2%)中,有可能在入院后的头两周内做出明确诊断。发热最常见的原因是感染,在51名儿童(64.5%)中发现,结核病和泌尿系统感染各占10例,最为常见。另有10名儿童被诊断为肿瘤性疾病(主要是白血病),7例(8.8%)患有胶原病。另有7名儿童病因未明确。死亡率为7.5%。临床病史和检查对诊断方向至关重要。这项研究的结果表明,对于所有出现不明原因发热的儿童,除了至少住院一周外,非常全面的问诊和临床检查对于确立诊断最为重要,同时根据检查结果对问题采取或多或少积极的处理方法。

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