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[儿童长期发热。67例回顾性研究]

[Prolonged fever in children. Retrospective study of 67 cases].

作者信息

Chouchane S, Chouchane C H, Ben Meriem C H, Seket B, Hammami S, Nouri S, Monastiri K, Guediche M N

机构信息

Service de pédiatrie, CHU Fattouma-Bourguiba, avenue 1(er) juin, 5000 Monastir, Tunisie.

出版信息

Arch Pediatr. 2004 Nov;11(11):1319-25. doi: 10.1016/j.arcped.2004.07.018.

Abstract

BACKGROUND

The first problem to face in prolonged fever is its etiologic diagnosis. Its incidence varies between 0,5 to 3% of all paediatric hospital-stay. Precise diagnosis need an extensive questionnary, complete physical examination and an algorithm of complementary exams.

PURPOSE

To precise the epidemiologic profile and causes of prolonged fever in a children.

POPULATION AND METHODS

Retrospective review of 67 children between two and 15 years old admitted in the general paediatrics department of the Fattouma Bourguiba university hospital in Monastir (Tunisia), for prolonged fever between 1(st) January 1988 and 31 December 1998.

RESULTS

The incidence of prolonged fever was 1,02%. The mean age was seven years with female predominance. The mean fever duration was 30 days. Fever was isolated in 23,9% of cases. Fever was associated to rheumatic or respiratory signs in respectively 26,9% and 20,9% of cases. Hospital-stay was of 11 days in 50% of cases. Prominent causes were dominated by infectious diseases (56,7%) with predominance of localized infections, followed by inflammatory diseases (20,9%) with predominance of rheumatic fever and neoplasms (3%). Fever remained of unknown origin was seen in 19,4% of cases.

CONCLUSION

Prolonged fever is still dominated by infectious and inflammatory diseases and depend on local epidemiological particularities. In fact we noted in this study the relative high-frequency of visceral leishmaniasis, complicated pulmonary hydatic cyst and rheumatic fever. The diagnosis approach should be based on complementary exams of first and second stage because of their high number and cost. Prognosis of fever of unknown origin is often favorable.

摘要

背景

长期发热面临的首要问题是病因诊断。其发病率在所有儿科住院病例中占0.5%至3%。准确诊断需要详细的问诊、全面的体格检查以及一系列辅助检查。

目的

明确儿童长期发热的流行病学特征及病因。

研究对象与方法

回顾性分析1988年1月1日至1998年12月31日期间在突尼斯莫纳斯提尔法图玛·布尔吉巴大学医院普通儿科住院的67例2至15岁长期发热儿童。

结果

长期发热的发病率为1.02%。平均年龄为7岁,女性居多。平均发热持续时间为30天。23.9%的病例仅有发热症状。发热分别与风湿或呼吸道症状相关的病例占26.9%和20.9%。50%的病例住院时间为11天。主要病因以传染病为主(56.7%),其中局部感染占优势,其次是炎症性疾病(20.9%),以风湿热为主,肿瘤占3%。19.4%的病例发热原因不明。

结论

长期发热仍以感染性和炎症性疾病为主,且取决于当地的流行病学特点。事实上,我们在本研究中注意到内脏利什曼病、复杂性肺包虫囊肿和风湿热的相对高发性。由于一期和二期辅助检查数量多且费用高,诊断方法应基于这些检查。不明原因发热的预后通常较好。

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