Estes S A, Yung C W
J Am Acad Dermatol. 1981 Jul;5(1):25-31. doi: 10.1016/s0190-9622(81)70073-2.
Two patients with delayed pressure urticaria were studied to define some of the physical parameters related to experimental lesion induction using a pressure-testing device. Graded pressures from 48 to 234 gm/mm2 were applied for 1 to 180 seconds on several anatomic areas. Experimentally induced lesions were symptomatically, clinically, and histologically identical to spontaneous wheals and reached a maximum size 9 hours after the stimulus. The threshold response found was related to the amount of pressure, the duration it was applied, and the anatomic area tested. Sites that previously reacted to pressure were refractory to additional stimuli for at least 24 to 48 hours. The mediator for delayed pressure urticaria remains unknown, and some patients do not respond to oral corticosteroids.
对两名迟发性压力性荨麻疹患者进行了研究，以确定一些与使用压力测试装置诱导实验性损伤相关的物理参数。在几个解剖区域施加48至234克/平方毫米的分级压力，持续1至180秒。实验诱导的损伤在症状、临床和组织学上与自发性风团相同，并在刺激后9小时达到最大尺寸。发现的阈值反应与压力大小、施加时间以及测试的解剖区域有关。先前对压力有反应的部位对额外刺激至少有24至48小时的不应期。迟发性压力性荨麻疹的介质仍然未知，一些患者对口服皮质类固醇无反应。
