Rudigoz R C, Arnaud M F, Dargent D, Magnin P
J Gynecol Obstet Biol Reprod (Paris). 1981;10(2):155-61.
Looking through a retrospective study of 28,828 deliveries the authors have been able to work out the frequency of thrombo-embolic complications of pregnancy (1 per 1000) and of the post-partum (3.95 per 1000). It is possible to point to different risk factors. Some are well known, these are varicose veins, Caesarean section, maternal age above 35. Other factors that are usually considered to be aetiological now appear to be less significant. These are: a history of previous thrombo-embolic conditions and post-partum sterilization. To be added to the classic risk factors are inhibition of lactation which, whatever procedure is used, significantly raises the incidence of thrombo-embolic complications. It would seem to be desirable, in view of these different parameters, that a risk score should be drawn up which would allow for medical treatment to be given prophylactically in the patients who are particularly exposed to risk.
通过对28828例分娩的回顾性研究,作者得以计算出妊娠血栓栓塞并发症的发生率(每1000例中有1例)和产后血栓栓塞并发症的发生率(每1000例中有3.95例)。可以指出不同的风险因素。一些是众所周知的,这些是静脉曲张、剖宫产、产妇年龄超过35岁。其他通常被认为是病因的因素现在似乎不太重要。这些因素包括:既往血栓栓塞病史和产后绝育。除了经典的风险因素外,抑制泌乳也会显著增加血栓栓塞并发症的发生率,无论采用何种方法。鉴于这些不同的参数,似乎应该制定一个风险评分,以便对特别容易发生风险的患者进行预防性药物治疗。