Farmer R G, Gulya A J, Whelan G
J Clin Gastroenterol. 1981 Mar;3(1):27-9.
We made an observational study of traveler's diarrhea in all members of a 48-person medical seminar group during a trip to Egypt and the Nile in September 1979. In addition to comparing symptoms in those who took antibiotic prophylaxis with doxycycline and those who did not, we also took into account water and dietary restrictions. Although our study supports the use of prophylactic doxycycline, the response appears to be considerably influenced by dietary or water restrictions. This study emphasizes the need to assess diet and water intake of travelers when conducting trials of medication aimed at preventing traveler's diarrhea.
1979年9月，我们对一个48人的医学研讨班小组全体成员在埃及和尼罗河之行期间的旅行者腹泻进行了一项观察性研究。除了比较服用强力霉素进行抗生素预防的人和未服用者的症状外，我们还考虑了水和饮食限制。尽管我们的研究支持使用预防性强力霉素，但反应似乎受到饮食或水限制的显著影响。这项研究强调，在进行旨在预防旅行者腹泻的药物试验时，有必要评估旅行者的饮食和水摄入量。
