Heck J E, Cohen M B
University of Cincinnati College of Medicine, Ohio.
Am Fam Physician. 1993 Oct;48(5):793-800, 805-6.
Traveler's diarrhea is the most common health problem in persons who visit developing countries. Dietary precautions are the mainstay of prevention. Since bacteria are responsible for 50 to 80 percent of cases of traveler's diarrhea, antibiotics are the drugs of choice for empiric therapy. Because bacteria are becoming increasingly resistant to trimethoprim-sulfamethoxazole and doxycycline, newer antibiotics, especially the fluoroquinolones, should be considered as first-line therapy. Antimotility agents may help reduce symptoms, but they should not be given to patients who have fever or bloody diarrhea. Antibiotic prophylaxis is recommended for certain high-risk individuals.
旅行者腹泻是前往发展中国家的人最常见的健康问题。饮食预防是预防的主要手段。由于细菌导致50%至80%的旅行者腹泻病例,抗生素是经验性治疗的首选药物。由于细菌对甲氧苄啶-磺胺甲恶唑和强力霉素的耐药性日益增加,应考虑使用更新的抗生素,尤其是氟喹诺酮类作为一线治疗药物。抗动力药物可能有助于减轻症状,但发热或血性腹泻患者不应使用。对于某些高危个体,建议进行抗生素预防。