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来自中欧、西班牙和苏格兰的小家鼠的罗伯逊易位变异。

Robertsonian variation in Mus musculus from Central Europe Spain, and Scotland.

作者信息

Adolph S, Klein J

出版信息

J Hered. 1981 May-Jun;72(3):219-21. doi: 10.1093/oxfordjournals.jhered.a109478.

DOI:10.1093/oxfordjournals.jhered.a109478
PMID:7276530
Abstract

Robertsonian translocations were found among mice captured on one of the Orkney islands in North Scotland, around Barcelona in Spain, and in Southern Germany around the cities of Tübingen and Ravensburg. Mice from Denmark, Poland, Astrachan in the Soviet Union Israel, and Egypt were found to be free of Robertsonian translocations. The Robertsonian variations in mice from Scotland and Spain are probably of independent origin and mostly likely also unrelated to the Alpine-Apennine system. On the other hand, the variation in mice from Southern Germany may be a part of the Alpine system. Hybrid zones were found near Barcelona and near Ravensburg. In the latter almost all the mice were heterozygous for at least one Robertsonian translocation, and often for several translocations. Three out of 14 typed mice were heterozygous for four metacentric chromosomes. The analysis revealed the existence of nine Robertsonian translocations not previously described: Rb(3.14)7Tu, Rb(4.10)8Tu, Rb(6.13)9Tu, and Rb(9.12)10Tu in Scotland; Rb(4.14)11Tu, Rb(6.10)13Tu, Rb(9.11)14Tu, and Rb(12.13)15Tu in Spain, and Rb(2.5)2Tu in Southern Germany.

摘要

在苏格兰北部的奥克尼群岛之一、西班牙巴塞罗那周边以及德国南部图宾根和拉文斯堡市周边捕获的小鼠中发现了罗伯逊易位。发现来自丹麦、波兰、苏联阿斯特拉罕、以色列和埃及的小鼠没有罗伯逊易位。来自苏格兰和西班牙的小鼠中的罗伯逊变异可能起源独立,很可能也与阿尔卑斯 - 亚平宁系统无关。另一方面,德国南部小鼠的变异可能是阿尔卑斯系统的一部分。在巴塞罗那附近和拉文斯堡附近发现了杂交带。在后者中,几乎所有小鼠至少有一个罗伯逊易位是杂合的,而且常常有几个易位是杂合的。在14只分型小鼠中有3只对4条中着丝粒染色体是杂合的。分析揭示了9种以前未描述过的罗伯逊易位的存在:苏格兰的Rb(3.14)7Tu、Rb(4.10)8Tu、Rb(6.13)9Tu和Rb(9.12)10Tu;西班牙的Rb(4.14)11Tu、Rb(6.10)13Tu、Rb(9.11)14Tu和Rb(12.13)15Tu;以及德国南部的Rb(2.5)2Tu。

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