马哈拉施特拉邦人群中的胎盘酶多态性：碱性磷酸酶和乳酸脱氢酶

Placental enzyme polymorphism among Maharashtrians: alkaline phosphatase and lactate dehydrogenase.

作者信息

Mukherjee B N, Das S K, Malhotra K C, Kate S L, Mutalik G S, Sainani G S, Bhidya S

出版信息

Ann Hum Biol. 1978 Sep;5(5):435-40. doi: 10.1080/03014467800003081.

Abstract

The distribution of placental alkaline phosphatase and lactate dehydrogenase types in 635 placentas from various endogamous groups of Maharashtra have been studied by starch gel electrophoresis. In the case of alkaline phosphatase, 6 common phenotypes and 6 rare phenotypes (F2I1, S1S2, S2S3, I1S2, F1S2, F1I2) are encountered. The highest frequency of Pls1 allele (0.7394) and lowest frequency of Pli1 allele (0.0246) have been found in the Nava-Budha. 6 cases of Cal-1 and 5 cases of Cal-2 types of LDH variants have been observed in the total samples, and Muslims possess the highest frequency of Cal-1 types (3.64%). Population groups are compared with respect to Pl alleles.

摘要

通过淀粉凝胶电泳研究了来自马哈拉施特拉邦不同同族群体的635份胎盘组织中胎盘碱性磷酸酶和乳酸脱氢酶类型的分布情况。就碱性磷酸酶而言，共发现6种常见表型和6种罕见表型（F2I1、S1S2、S2S3、I1S2、F1S2、F1I2）。在纳瓦 - 布达族中发现Pls1等位基因频率最高（0.7394），Pli1等位基因频率最低（0.0246）。在全部样本中观察到6例Cal - 1型和5例Cal - 2型乳酸脱氢酶变体，穆斯林群体中Cal - 1型频率最高（3.64%）。对各人群组的Pl等位基因进行了比较。