Kulakov V I, Kulikova N N, Minasova G S, Smekuna F A
Antibiotiki. 1978 Dec;23(12):1108-12.
Features of absorption, distribution and excretion of methicillin, oxacillin and cephaloridine in 58 puerpera were studied. No complications were observed in the postnatal period of the puerpera. The results of the study of the antibiotic pharmacokinetics provided elaboration of the optimal regimen for the use of methicillin, oxacillin and cephaloridine in puerpera, i. e. I g intramuscularly every 6 hours.
对58例产妇体内甲氧西林、苯唑西林和头孢菌素的吸收、分布及排泄特征进行了研究。这些产妇产后未观察到并发症。抗生素药代动力学研究结果为产妇使用甲氧西林、苯唑西林和头孢菌素的最佳用药方案提供了详细说明,即每6小时肌肉注射1克。