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[兔模型中纤维蛋白组织粘合剂在结膜和巩膜手术中的实验结果(作者译)]

[Experimental findings with a fibrin tissue adhesive in conjunctival and skleral surgery in a rabbit model (author's transl)].

作者信息

Härting F, Mellin K B

出版信息

Klin Monbl Augenheilkd. 1981 Jul;179(1):23-5. doi: 10.1055/s-2008-1057252.

Abstract

The authors investigated the wound closure of conjunctival wounds with fibrin adhesive as compared to a suture technique in rabbits. Similarly, the fixation of a transplant of lyophilized dura mater on the sclera by fibrin adhesive was also compared with a suture technique. Both clinically and histologically, there were only negligible differences in wound healing in the two series. In particular, no toxic reaction caused by the adhesive substance was observed. To avoid failures in wound closure with the investigated tissue adhesive there must be no tension at the edges of the wound.

摘要

作者在兔身上研究了与缝合技术相比,使用纤维蛋白粘合剂对结膜伤口进行的伤口闭合情况。同样,还比较了用纤维蛋白粘合剂将冻干硬脑膜移植物固定在巩膜上与缝合技术的效果。在临床和组织学方面,两个系列的伤口愈合仅有微不足道的差异。特别是,未观察到由粘合剂物质引起的毒性反应。为避免在所研究的组织粘合剂用于伤口闭合时出现失败情况,伤口边缘必须无张力。

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