Sritharan V, Venkatesan K, Bharadwaj V P, Girdhar B K
Lepr India. 1981 Jul;53(3):437-42.
While leprosy does not primarily affect the kidneys, secondary involvement of kidneys has been reported in lepromatous leprosy and especially in lepra-reaction. In the present study the authors have investigated the functional status of the kidneys of lepromatous leprosy patients by focussing attention to parameters like acidification of urine, glomerular filtration rate and excretion of a foreign dye administered intramuscularly. This study revealed a decreased ability to acidify urine and to excrete the dye as well as a drop in glomerular filtration rate in untreated LL patients. The said disturbances were more pronounced in lepra reaction.
虽然麻风病主要不影响肾脏，但在瘤型麻风病中，尤其是在麻风反应中，已有肾脏继发性受累的报道。在本研究中，作者通过关注尿液酸化、肾小球滤过率以及肌肉注射外源染料的排泄等参数，对瘤型麻风病患者的肾脏功能状态进行了研究。这项研究表明，未经治疗的瘤型麻风病患者尿液酸化和排泄染料的能力下降，同时肾小球滤过率降低。上述紊乱在麻风反应中更为明显。
