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人体自动除颤。初步手术经验。

Automatic defibrillation in man. The initial surgical experience.

作者信息

Watkins L, Mirowski M, Mower M M, Reid P R, Griffith L S, Vlay S C, Weisfeldt M L, Gott V L

出版信息

J Thorac Cardiovasc Surg. 1981 Oct;82(4):492-500.

PMID:7278341
Abstract

The automatic implantable defibrillator is an electronic device designed to detect and promptly correct malignant ventricular arrhythmias. Nineteen patients, all survivors of multiple cardiac arrests because of ventricular arrhythmias unresponsive to therapy, have undergone implantation of the automatic defibrillator. In seven patients who had had a previous cardiac operation, implantation was performed through a left lateral thoracotomy. A median sternotomy was used in five patients without a previous operation. In six patients cardiac procedures were performed concomitantly with defibrillator implantation. There were no operative deaths. The average follow-up is 6 months, the longest being 14 months. Following implantation, 47 episodes of malignant ventricular arrhythmias were documented. Twenty-six occurred spontaneously (17 of them outside the hospital); all were corrected with a single 25 joule pulse. Seventeen of 21 arrhythmias induced postoperatively were terminated. Although further validation is required, this study demonstrates that the automatic defibrillator is capable of diagnosing and terminating potentially lethal ventricular arrhythmias. Finally, implantation can be safely accomplished in an exceedingly high risk population.

摘要

植入式自动除颤器是一种电子装置,旨在检测并迅速纠正恶性室性心律失常。19名患者均因室性心律失常导致多次心脏骤停且对治疗无反应,但均存活下来,他们接受了植入式自动除颤器植入手术。7名曾接受过心脏手术的患者,通过左外侧开胸进行植入。5名未接受过手术的患者采用正中胸骨切开术。6名患者在植入除颤器的同时进行了心脏手术。无手术死亡病例。平均随访时间为6个月,最长为14个月。植入后,记录到47次恶性室性心律失常发作。26次为自发发作(其中17次发生在院外);所有发作均通过单次25焦耳脉冲纠正。术后诱发的21次心律失常中有17次被终止。尽管还需要进一步验证,但本研究表明植入式自动除颤器能够诊断并终止潜在致命的室性心律失常。最后,在极高风险人群中也可安全地完成植入手术。

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