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新月弯孢霉与实验性暗色丝孢霉病

Curvularia lunata in experimental phaeohyphomycosis.

作者信息

Whitcomb M P, Jeffries C D, Weise R W

出版信息

Mycopathologia. 1981 Aug 7;75(2):81-8. doi: 10.1007/BF00505782.

DOI:10.1007/BF00505782
PMID:7278939
Abstract

Curvularia lunata strain SP, isolated from a disseminated human infection, infected normal mice, but three other strains of C. lunata and one each of C. pallescens and C. spicifera did not. The SP strain was recovered in cultures from, and hyphal filaments were observed in, abscesses in the liver and spleen of experimentally infected mice. All strains of Curvularia infected mice treated with 400 rads X-irradiation and 10.0 mg cortisone, but at 400 rads and 5.0 mg only two strains of C. lunata (SP and Ghosh) and C. pallescens and C. spicifera infected mice. At 200 rads and 10.0 mg, C. lunata Sp, C. pallescens and C. spicifera; and at 200 rads and 5.0 mg, only C. lunata SP and C. pallescens caused infection. After X-irradiation (200 or 400 rads) or cortisone (5.0 or 10.0 mg) alone only C. lunata SP caused infections in mice.

摘要

从一例播散性人类感染中分离出的新月弯孢菌SP菌株可感染正常小鼠,但其他三株新月弯孢菌以及一株苍白弯孢菌和一株穗状弯孢菌则不能。在实验感染小鼠的肝脏和脾脏脓肿的培养物中可分离到SP菌株,且观察到了菌丝。所有新月弯孢菌菌株均可感染经400拉德X射线照射并给予10.0毫克可的松处理的小鼠,但在400拉德和5.0毫克剂量时,只有两株新月弯孢菌(SP和戈什菌株)、苍白弯孢菌和穗状弯孢菌能感染小鼠。在200拉德和10.0毫克剂量时,新月弯孢菌SP菌株、苍白弯孢菌和穗状弯孢菌可感染小鼠;在200拉德和5.0毫克剂量时,只有新月弯孢菌SP菌株和苍白弯孢菌能引起感染。单独进行X射线照射(200或400拉德)或给予可的松(5.0或10.0毫克)后,只有新月弯孢菌SP菌株能感染小鼠。

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本文引用的文献

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Cortisone and roentgen radiation in combination as synergistic agents for production of lethal infections.可的松与X射线辐射联合作为产生致死性感染的协同剂。
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Effect of x-rays on immunity; a review.X射线对免疫的影响;综述
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Mycotic keratitis caused by Curvularia lunata var. aeria.新月弯孢菌气生变种引起的真菌性角膜炎。
Mycopathologia. 1986 Jan;93(1):9-12. doi: 10.1007/BF00437007.
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Mycetomas caused by Curvularia lunata, Madurella grisea, Aspergillus nidulans, and Nocardia brasiliensis in Sudan.苏丹由新月弯孢霉、灰马杜拉放线菌、构巢曲霉和巴西诺卡菌引起的足菌肿。
Sabouraudia. 1973 Jul;11(2):179-82.
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