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[正常压力脑积水。56例患者的术前及术后研究(作者译)]

[Normal pressure hydrocephalus. Pre- and postoperative study of 56 cases (author's transl)].

作者信息

Janny P, Colnet G, Veyre A, Chazal J, Barretto L C

出版信息

Neurochirurgie. 1981;27(2):89-96.

PMID:7279095
Abstract

56 patients considered to have a low pressure hydrocephalus were treated between 1973 and 1979 by a ventriculo-atrial shunting, using a medium pressure Holter valve. Apart from a standard clinical examination, these patients underwent a pneumoencephalography, an isotope cisternography, a measurement of ventricular pressure, and a determination of the C.S.F. resistance to flow by mean of an infusion test. A 6 months to 5 years follow up study showed that the operative result could be considered a success in 47%, a failure in 53%. No precise correlation could be found between any clinical sign or response to investigations, and the functional results. However, an early and really unsteady gait, an important ventricular enlargement without image of cortical atrophy, and the presence of pressure waves on I.C.P. recordings, seem to be frequently associated with good results.

摘要

1973年至1979年间,56例被认为患有低压性脑积水的患者接受了脑室-心房分流术,使用的是中压霍尔特瓣膜。除了标准的临床检查外,这些患者还接受了气脑造影、同位素脑池造影、脑室压力测量以及通过输液试验测定脑脊液的流动阻力。一项为期6个月至5年的随访研究表明,手术结果在47%的患者中可被视为成功,在53%的患者中则为失败。在任何临床体征或检查反应与功能结果之间均未发现确切的相关性。然而,早期且真正不稳定的步态、无皮质萎缩影像的重要脑室扩大以及颅内压记录上出现压力波,似乎常常与良好的结果相关。

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