Vezina J L
Neurochirurgie. 1981;27 Suppl 1:19-28.
Radiologic studies of the sella turcica have been performed in 355 patients operated on for prolactinomas. According to our classification, the grading of the sella in 300 females was normal in seventeen, grade I in one hundred and seventy-eight, grade II in eighty-seven, grade III in nine and grade IV in nine. A suprasellar expansion was evidenced in twenty-four of these patients. In 55 men, the sella was of grade I in eight, grade II in thirty-nine and grade IV in eight. Twenty-three had a suprasellar expansion. The early radiological diagnosis of a prolactin-secreting microadenoma became important when the hypophyseal origin of the clinical syndromes associated with hyperprolactinemia was demonstrated. Prolactinomas can usually be diagnosed by polytomography when they have reached 4 mm in size. Subtle bony changes such as cortical thinning, lateralized blistering or bulging of the floor are reliable radiological signs when associated with a biologically confirmed clinical syndrome.
对355例因泌乳素瘤接受手术治疗的患者进行了蝶鞍的放射学研究。根据我们的分类，300例女性患者中，蝶鞍分级正常的有17例，I级的有178例，II级的有87例，III级的有9例，IV级的有9例。其中24例患者有鞍上扩展。在55例男性患者中，蝶鞍I级的有8例，II级的有39例，IV级的有8例。23例有鞍上扩展。当与高泌乳素血症相关的临床综合征的垂体起源得到证实时，泌乳素分泌性微腺瘤的早期放射学诊断变得很重要。当泌乳素瘤大小达到4毫米时，通常可以通过断层摄影术进行诊断。与经生物学证实的临床综合征相关时，诸如皮质变薄、底部侧方水疱样改变或膨出等细微骨质改变是可靠的放射学征象。
