Bergener M, Hesse C
Neurosurg Rev. 1980;3(4):251-6. doi: 10.1007/BF01650030.
A multidimensional concept of diagnosis and treatment of mental disorders is presented. Major contributions to basic research come from pharmacological experiments. Clinical outcome in treatment of endogenous depression can be assessed by rating scales and psychophysiological tests and correlated with the serum level of drug. In the case of maprotiline there seems to be a correlation between serum level and clinical outcome.
本文提出了精神障碍诊断与治疗的多维概念。基础研究的主要贡献来自药理学实验。内源性抑郁症治疗的临床结果可通过评定量表和心理生理学测试进行评估,并与药物血清水平相关联。就马普替林而言,血清水平与临床结果之间似乎存在相关性。