Bobbio Pallavicini E, Luliri P, Burgio V L
Minerva Med. 1981 Sep 29;72(37):2473-8.
A 39-year-old woman was hospitalized at our Institute following a diagnosis of "suspected systemic lymphopathy". The patient exhibited mediastinal tumefaction, moderate anemia, thrombocytopenia, leucoerythroblastic streak in peripheral blood, diffuse bone pain, slight fever, cough and dyspnea. The clinical picture, radiological findings and hematochemical data apparently suggested a diagnosis of epithelial neoplasia of bronchial origin, or a primary hemopathy. Only by means of an osteomedullary biopsy was it possible to establish that the disease was actually a bronchogenic carcinoma invading the marrow. In conclusion, both for a correct staging of patients with carcinoma, and for histological diagnosis, when the primary side can not be identified or attacked, the osteomedullary biopsy, if feasible carried out at different sites, proves to be the test of choice.
一名39岁女性因诊断为“疑似系统性淋巴结病”入住我院。患者表现为纵隔肿胀、中度贫血、血小板减少、外周血中出现幼稚粒-幼红细胞血象、弥漫性骨痛、低热、咳嗽和呼吸困难。临床表现、影像学检查结果和血液生化数据明显提示诊断为支气管源性上皮肿瘤或原发性血液病。只有通过骨髓活检才能确定该疾病实际上是侵袭骨髓的支气管癌。总之，对于癌症患者的准确分期以及组织学诊断，当无法确定或触及原发部位时，如果可行，在不同部位进行骨髓活检被证明是首选的检查方法。
