López Encuentra A, Sueiro Bendito A, Cortés-Funes H
Med Clin (Barc). 1979 Oct 10;73(6):222-7.
The results of a prospective study on bronchogenic carcinoma are analyzed. The most frequent metastatic localization being the bone (24 percent), followed by the brain (21 percent) and the pleura (20 percent). The type which most frequently metastatized to the brain is the epidermoid carcinoma. The as yet unresolved difficulties in the diagnosis of metastasis to the adrenal glands as well as to the liver are pointed out, conducting a comparative study with data from necropsies in order to corroborate such defficiencies. We systematically practiced radioisotope bone scanning, eliminating the bone radiography and carrying it out only in areas with pathologic isotopic uptake. Biopsy of the iliac crest should be performed in all cases of undifferentiated small-cell type, although this is not necessary with the other histopathologic types. Finally, the criteria for the identification of liver metastasis, in the absence of more proper pilot studies, should be the same as those established in 1974; physical examination and determination of hepatic enzymes; if the results are abnormal, a liver scanning should be indicated, and if it is normal, it will be necessary to perform a liver biopsy by peritoneoscopy.
对一项关于支气管源性癌的前瞻性研究结果进行了分析。最常见的转移部位是骨骼（24%），其次是脑（21%）和胸膜（20%）。最常转移至脑的类型是表皮样癌。指出了肾上腺和肝脏转移诊断中尚未解决的困难，并与尸检数据进行比较研究以证实这些不足。我们系统地进行放射性核素骨扫描，取消骨X线摄影，仅在同位素摄取异常的部位进行。所有未分化小细胞型病例均应进行髂嵴活检，不过其他组织病理学类型则无需如此。最后，在没有更合适的初步研究的情况下，肝转移的识别标准应与1974年制定的相同；体格检查和肝酶测定；如果结果异常，应进行肝脏扫描，如果正常，则有必要通过腹腔镜进行肝活检。
