Lebedev S P, Mukhin A S
Arkh Patol. 1978;40(8):65-7.
Approaches for the diagnosis of alcoholic cirrhosis of the liver at the dissecting table are given on the basis of the analysis of autopsy materials and liver biopsies. The etiological verification of cirrhosis is based on the peculiar morphological lesions of the liver and other organs. The liver is enlarged, its surface micronodal; histologically, an attack of acute alcoholic hepatitis is found not infrequently: necroses of hepatocytes, predominantly neutrophilic infiltration of the stroma and necrotic zones, alcoholic hyalin. Due to autolysis, alcoholic hyalin in the autopsy material changes somehow and is hardly detectable. A combination of alcoholic cirrhosis of the liver with alcoholic cardiopathy and/or chronic calcifying pancreatitis is typical.
基于尸检材料和肝活检分析,给出了在解剖台上诊断酒精性肝硬化的方法。肝硬化的病因学验证基于肝脏和其他器官的特殊形态学病变。肝脏肿大,表面呈小结节状;组织学上,急性酒精性肝炎发作并不少见:肝细胞坏死,主要是间质和坏死区的中性粒细胞浸润,酒精性透明小体。由于自溶作用,尸检材料中的酒精性透明小体有所变化,难以检测到。酒精性肝硬化合并酒精性心肌病和/或慢性钙化性胰腺炎是典型的。